Pain can be caused by a wide variety of conditions, including inflammation or neurological disorders. Neuropathic pain is related to the abnormal function of the nervous system. It is often a long-lasting and debilitating condition and frequently is associated with diabetic peripheral neuropathy and shingles.

Pain is the number one reason people seek healthcare treatment. In the U.S., more than 50 million people suffer from chronic pain, including both inflammatory and neuropathic pain.