Amgen data includes specific measurements for energy, water and waste obtained from our operations, representing 88 percent of Amgen's worldwide facility space based on total square feet. Included facilities are in Thousand Oaks, California, U.S.; West Greenwich, Rhode Island, U.S.; Louisville, Kentucky, U.S.; South San Francisco, California, U.S.; Cambridge and Woburn, Massachusetts, U.S.; Juncos, Puerto Rico; Burnaby, Canada; Breda, Netherlands; Dun Laoghaire, Ireland; Uxbridge and Cambridge, United Kingdom; São Paulo, Brazil; Yenibosna and Sekerpinar, Turkey; and Tuas, Singapore. Energy and carbon data for the remaining 12 percent of facility space is estimated based on building energy intensity factors and country specific emission factors. This includes leased buildings where we have operational control over building infrastructure, including utilities.
Measurement and verification of conservation and reduction projects for energy and carbon, water and waste are based on adaptation of the International Performance Measurement and Verification Protocol (IPMVP). Project measurements are conducted using reasonable means, including direct measurements and scientific estimations as appropriate. Values for conservation and reduction projects represent year-over-year, cumulative and continuing avoidance based on a 2007 baseline, then re-baselined in 2012 to match the next-generation 2020 Target design.