At Amgen, Research & Development (R&D) is rooted in the belief that for every patient there is a solution.

From oncology to rare disease to inflammation and cardiometabolic disease and more, we work tirelessly to identify potential new therapies and improve existing treatments.

Amgen R&D combines a unique understanding of human genetics and disease biology with advanced technologies like protein engineering and artificial intelligence (AI) to identify the most effective modalities to meet patients' needs.

We use our expertise and data to enhance care, developing precision medicines informed by the biology of patients and diseases.

We're reimagining how clinical trials are conducted, leveraging new technologies and approaches to protocol design to make them more efficient and more representative of the patients who will take our medicines.

Fueled by our scientific curiosity and out-of-the-box thinking, we're committed to bringing new medicines to patients faster than ever before.

OUR SCIENCE

Human & Disease Biology

We collect and analyze data – including genomics (genes), transcriptomics (RNA) and proteomics (proteins) – to better understand disease, identify biomarkers and rapidly screen targets to design promising new molecules, aiming to achieve higher success rates and faster timelines.

Novel Targets & Modalities

We use our deep understanding of human and disease biology to identify novel targets and design the next generation of therapeutics, building on Amgen’s proven leadership in engineering molecules. From complex biotherapeutics and modular multispecifics to gene-silencing siRNA therapeutics and small molecules that address difficult targets, we work to determine the most effective modalities to fight conditions that were previously untreatable.

Clinical Trial Optimization

We are delivering on the promise of medicines by optimizing clinical trial design and implementation. We leverage real-world data along with data analytics and AI to design faster, more efficient, more accessible trials – and we adapt trial protocols based on our real-time observations. This approach has more than doubled our enrollment at clinical trial sites.

AI in Research & Development

AI enables us to move from molecule to medicine more quickly and efficiently, leading to enormous potential for the patients we serve. The power of AI is accelerating population data analysis, leading to faster drug discovery and development, enabling us to bring innovative medicines to patients faster than ever before.

There's a place for you

Discovering the next generation of medicines at Amgen begins with a team of individuals dedicated to expanding knowledge of human and disease biology.

We’ve been consistently recognized by industry leaders as a great place to work, having been named one of America's Best Large Employers by Forbes magazine, as well as one of the World's 25 Best Workplaces™ by Fortune and Great Place to Work®.

LEARN MORE ABOUT CAREERS IN R&D